Structure of PDB 8k2b Chain v

Receptor sequence
>8k2bv (length=69) Species: 9606 (Homo sapiens) [Search protein sequence]
APWSREAVLSLYRALLRQGRQLRYTDRDFYFASIRREFRKNQKLEDAEAR
ERQLEKGLVFLNGKLGRII
3D structure
PDB8k2b Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Chainv
Resolution3.4 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PNS v P3 R6 N42 Q43 E46 A50 R51 Q54 P2 R5 N41 Q42 E45 A49 R50 Q53
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0140978 mitochondrial large ribosomal subunit binding
Biological Process
GO:0000266 mitochondrial fission
GO:0006417 regulation of translation
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0042254 ribosome biogenesis
GO:0070131 positive regulation of mitochondrial translation
GO:1902775 mitochondrial large ribosomal subunit assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8k2b, PDBe:8k2b, PDBj:8k2b
PDBsum8k2b
PubMed38942792
UniProtL0R8F8|MIDUO_HUMAN Mitochondrial ribosome and complex I assembly factor AltMIEF1 (Gene Name=MIEF1)

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