Structure of PDB 8ifc Chain v

Receptor sequence

>8ifcv (length=78) Species: 562 (Escherichia coli) [Search protein sequence]

GSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDH
TLFAKADGKVKFEVKGPKNRKFISIEAE

3D structure

PDB

8ifc Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside.

Chain

Resolution

2.9 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	v	N12 R14 D15 S16 E17 A18 K19 R20 R25 F26 G27 E29 A33 G34 S35 I36 R41 G42 T43 K44 H46 G54 R55 D56 H57 T58 F60 F69 R77 K78	N5 R7 D8 S9 E10 A11 K12 R13 R18 F19 G20 E22 A26 G27 S28 I29 R34 G35 T36 K37 H39 G47 R48 D49 H50 T51 F53 F62 R70 K71
BS02	rna	v	G73 P74 N76	G66 P67 N69

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019843	rRNA binding
GO:0043022	ribosome binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0001558	regulation of cell growth
GO:0002181	cytoplasmic translation
GO:0006412	translation
GO:0042256	cytosolic ribosome assembly
GO:0090070	positive regulation of ribosome biogenesis
GO:1902626	assembly of large subunit precursor of preribosome

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:8ifc, PDBe:8ifc, PDBj:8ifc
PDBsum	8ifc
PubMed	38227611
UniProt	P0A7L8\|RL27_ECOLI Large ribosomal subunit protein bL27 (Gene Name=rpmA)