Structure of PDB 8c3a Chain v

Receptor sequence

>8c3av (length=203) Species: 5476 (Candida albicans) [Search protein sequence]

GAYKYLEELQRKKQSDVMRFLYRVRCWEYRQKNVIHRASRPSRPDKARRL
GYKAKQGFVIYRIRVRRGGRKRPVPKGATYGKPTNQGVNQLKYQKSLRST
AEERVGRRASNLRVLNSYWVNQDSTYKYFEVILVDPSHKAIRRDARYNWI
VNPVHKHREARGLTSAGKKSRGINKGHLFNKTKAGRRHTWKKHNTLSLWR
YRS

3D structure

PDB

8c3a New crystal system to promote screening for new eukaryotic inhibitors

Chain

Resolution

3.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	v	G2 Y4 K5 E8 R12 K14 Q15 R20 R24 R31 Q32 N34 V35 S40 R41 R44 K47 R49 R50 L51 K54 A55 K56 Q57 R67 R68 G69 G70 R71 K72 R73 P74 P76 K77 G78 Y81 G82 K83 P84 T85 N86 Q87 V89 N90 Q91 K93 Y94 Q95 K96 S97 L98 R99 R105 R108 S111 N112 N117 W120 Q123 S125 Y127 K128 S138 H139 K140 A141 R144 R147 W150 P154 V155 H156 K157 A161 R162 L164 S166 K170 S171 R172 I174 K176 G177 H178 L179 F180 N181 K182 R187 R188 H189 W191 H194 S198 W200 R201 Y202 R203	G1 Y3 K4 E7 R11 K13 Q14 R19 R23 R30 Q31 N33 V34 S39 R40 R43 K46 R48 R49 L50 K53 A54 K55 Q56 R66 R67 G68 G69 R70 K71 R72 P73 P75 K76 G77 Y80 G81 K82 P83 T84 N85 Q86 V88 N89 Q90 K92 Y93 Q94 K95 S96 L97 R98 R104 R107 S110 N111 N116 W119 Q122 S124 Y126 K127 S137 H138 K139 A140 R143 R146 W149 P153 V154 H155 K156 A160 R161 L163 S165 K169 S170 R171 I173 K175 G176 H177 L178 F179 N180 K181 R186 R187 H188 W190 H193 S197 W199 R200 Y201 R202
BS02	rna	v	R38 Q57 V60 Y62 R109 N112 D136 H139	R37 Q56 V59 Y61 R108 N111 D135 H138
BS03	MG	v	G186 R187 R188 H189	G185 R186 R187 H188

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:1990904	ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:8c3a, PDBe:8c3a, PDBj:8c3a
PDBsum	8c3a
PubMed
UniProt	Q5A6R1\|RL15A_CANAL Large ribosomal subunit protein eL15 (Gene Name=RPL15A)

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