Structure of PDB 8a3l Chain v

Receptor sequence

>8a3lv (length=84) Species: 83333 (Escherichia coli K-12)

AHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANV
GCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE

3D structure

• PDB: 8a3l Structural insights into the binding of bS1 to the ribosome.
• Chain: v
• Resolution: 3.42 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	v	A2 H3 K4 K5 S9 T10 N12 R14 D15 S16 E17 A18 K19 R20 L21 K24 R25 F26 G27 E29 L32 A33 G34 S35 I36 R41 G42 T43 F45 H46 G54 R55 D56 H57 T58 F60 F69 K75 R77 K78	A1 H2 K3 K4 S8 T9 N11 R13 D14 S15 E16 A17 K18 R19 L20 K23 R24 F25 G26 E28 L31 A32 G33 S34 I35 R40 G41 T42 F44 H45 G53 R54 D55 H56 T57 F59 F68 K74 R76 K77
BS02	rna	v	G73 P74	G72 P73

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding
• GO:0019843 rRNA binding
• GO:0043022 ribosome binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0001558 regulation of cell growth
• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0042256 cytosolic ribosome assembly
• GO:0090070 positive regulation of ribosome biogenesis
• GO:1902626 assembly of large subunit precursor of preribosome

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8a3l, PDBe:8a3l, PDBj:8a3l
• PDBsum: 8a3l
• PubMed: 36840711
• UniProt: P0A7L8|RL27_ECOLI Large ribosomal subunit protein bL27 (Gene Name=rpmA)