Structure of PDB 8h0w Chain u

Receptor sequence

>8h0wu (length=73) Species: 9606 (Homo sapiens) [Search protein sequence]

PPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSL
VSKGTLVQTKGTGASGSFKLNKK

3D structure

PDB

8h0w Structural basis of RNA polymerase II transcription on the chromatosome containing linker histone H1.

Chain

Resolution

4.6 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	u	V40 S58 R79 K97 S104	V3 S21 R42 K60 S67

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003690	double-stranded DNA binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0030527	structural constituent of chromatin
GO:0031490	chromatin DNA binding
GO:0031492	nucleosomal DNA binding

	Biological Process
GO:0000122	negative regulation of transcription by RNA polymerase II
GO:0006325	chromatin organization
GO:0006334	nucleosome assembly
GO:0006357	regulation of transcription by RNA polymerase II
GO:0030261	chromosome condensation
GO:0045910	negative regulation of DNA recombination

External links