Structure of PDB 7pfw Chain u

Receptor sequence

>7pfwu (length=75) Species: 9606 (Homo sapiens) [Search protein sequence]

SGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLK
SLVSKGTLVQTKGTGASGSFKLNKK

3D structure

PDB

7pfw Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory.

Chain

Resolution

5.2 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	u	P38 V39 R53 S57 K63 R78 S103	P4 V5 R19 S23 K29 R44 S69
BS02	dna	u	K80 A100	K46 A66

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003690	double-stranded DNA binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0030527	structural constituent of chromatin
GO:0031490	chromatin DNA binding
GO:0031492	nucleosomal DNA binding
GO:0042826	histone deacetylase binding

	Biological Process
GO:0000122	negative regulation of transcription by RNA polymerase II
GO:0006325	chromatin organization
GO:0006334	nucleosome assembly
GO:0006357	regulation of transcription by RNA polymerase II
GO:0030261	chromosome condensation
GO:0045910	negative regulation of DNA recombination

External links