Structure of PDB 7pft Chain u

Receptor sequence

>7pftu (length=75) Species: 9606 (Homo sapiens) [Search protein sequence]

SGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLK
SLVSKGTLVQTKGTGASGSFKLNKK

3D structure

PDB

7pft Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory.

Chain

Resolution

9.8 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	u	P38 R53 K80 A100	P4 R19 K46 A66
BS02	dna	u	S35 V39 S57 K63 K74 N75 R78 L81 S103	S1 V5 S23 K29 K40 N41 R44 L47 S69

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003690	double-stranded DNA binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0030527	structural constituent of chromatin
GO:0031490	chromatin DNA binding
GO:0031492	nucleosomal DNA binding
GO:0042826	histone deacetylase binding

	Biological Process
GO:0000122	negative regulation of transcription by RNA polymerase II
GO:0006325	chromatin organization
GO:0006334	nucleosome assembly
GO:0006357	regulation of transcription by RNA polymerase II
GO:0030261	chromosome condensation
GO:0045910	negative regulation of DNA recombination

External links