Structure of PDB 6zym Chain u

Receptor sequence
>6zymu (length=157) Species: 9606 (Homo sapiens) [Search protein sequence]
SERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIY
KGKKFNARKETVQNEVYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTME
HGATRNFQLNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEA
MLRQHRL
3D structure
PDB6zym Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome.
Chainu
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna u R4 K5 K9 K22 R3 K4 K8 K21
BS02 rna u R34 Y51 G53 K55 N57 K79 R33 Y50 G52 K54 N56 K78
BS03 rna u R4 R34 K60 R3 R33 K59
BS04 rna u E3 R4 E2 R3
BS05 peptide u D14 F15 P21 L23 V32 D13 F14 P20 L22 V31
BS06 ZN u C43 C46 C80 C83 C42 C45 C79 C82
Gene Ontology
Biological Process
GO:0000398 mRNA splicing, via spliceosome

View graph for
Biological Process
External links
PDB RCSB:6zym, PDBe:6zym, PDBj:6zym
PDBsum6zym
PubMed33007253
UniProtQ9BW85|YJU2_HUMAN Splicing factor YJU2 (Gene Name=YJU2)

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