Structure of PDB 6g4w Chain u

Receptor sequence
>6g4wu (length=628) Species: 9606 (Homo sapiens) [Search protein sequence]
LSRVDQRHRASQLRKQKKEAVLAEKRQLGGKDGPPHQVLVVPLHSRISLP
EAMQLLQDGTVHLNELGNTQNFMLLCPRLKHRWFFTSARPGDLHVVLDMA
KVADTILFLLDPLEGWDSTGDYCLSCLFAQGLPTYTLAVQGISGLPLKKQ
IDTRKKLSKAVEKRFPHDKLLLLDTQQEAGMLLRQLANQKQQHLAFRDRR
AYLFAHAVDFVPSEENNLVGTLKISGYVRGQTLNVNRLLHIVGYGDFQMK
QIDAPGDPFPLNPKVLMKADPGRQESLQAEVIPDPKVPKGTSSYQAEWID
EEAEAKMLEKYKQERLEEMFPDEVDTPRDVAARIRFQKYRGLKSFRTSPW
DPKENLPQDYARIFQFQNFTNTRKSIFKEVEEKEVEGAEVGWYVTLHVSE
VPVSVVECFRQGTPLIAFSLLPHEQKMSVLNMVVRRDPGNTEPVKAKEEL
IFHCGFRRFRASPLFSQHTAADKHKLQRFLTADMALVATVYAPITFPPAS
VLLFKQKSNGMHSLIATGHLMSVDPDRMVIKRVVLSGHPFKIFTKMAVVR
YMFFNREDVLWFKPVELRTKWGRRGHIKEPLGTHGHMKCSFDGKLKSQDT
VLMNLYKRVFPKWTYDPYVPEPVPWLKS
3D structure
PDB6g4w Visualizing late states of human 40S ribosomal subunit maturation.
Chainu
Resolution4.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna u S49 R50 N238 T747 S2 R3 N188 T583
BS02 peptide u K517 I527 F528 Q529 Q531 W725 K353 I363 F364 Q365 Q367 W561
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0030688 preribosome, small subunit precursor

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6g4w, PDBe:6g4w, PDBj:6g4w
PDBsum6g4w
PubMed29875412
UniProtQ2NL82|TSR1_HUMAN Pre-rRNA-processing protein TSR1 homolog (Gene Name=TSR1)

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