Structure of PDB 6fec Chain u

Receptor sequence

>6fecu (length=76) Species: 9606 (Homo sapiens) [Search protein sequence]

YTAFLGNLPYDVTEESIKEFFRGLNISAVRLPREPSNPERLKGFGYAEFE
DLDSLLSALSLNEESLGNRRIRVDVA

3D structure

PDB

6fec Structure of a human cap-dependent 48S translation pre-initiation complex.

Chain

Resolution

6.3 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	u	P32 R40 K42	P32 R40 K42

Gene Ontology

	Molecular Function
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0003743	translation initiation factor activity
GO:0005515	protein binding

	Biological Process
GO:0006412	translation
GO:0006413	translational initiation
GO:0006446	regulation of translational initiation

	Cellular Component
GO:0005829	cytosol
GO:0016281	eukaryotic translation initiation factor 4F complex

External links

PDB	RCSB:6fec, PDBe:6fec, PDBj:6fec
PDBsum	6fec
PubMed	29401259
UniProt	P23588\|IF4B_HUMAN Eukaryotic translation initiation factor 4B (Gene Name=EIF4B)