Structure of PDB 5jcs Chain u

Receptor sequence
>5jcsu (length=373) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
KDKNILQESVLNKYRTAGQIAQTALKYVTSLINDSYHSKTTQRQLTVPEL
CLLTDSFILTRLEQYYKNKVNERGIAIPTTIDIDQISGGWCPEIDVTGTL
RPGDLVKITLGVHIDGYTSEVSHTMVIYPVDETKPILQPTGPLLGGKADA
VAAAHIAMETVVALSSGITGQLIRTIVDTIARSYNCGVVPGSRVRRIRRF
LAGQNEGIVAFTNVSAIPSDDFVVQSGEVYLIDLKMASLHKAGELIARPG
AYVRDFAQTHILKLKTSRQLLTKIDKQGVYPFKLSHLKSFRLGMSEISNN
YLCVESPIQIATSTVARECNTIVLCDSSVSTTDRPELLRLTGGSKTCQPS
WIHSQHELNPQDSIVQGIFQLAT
3D structure
PDB5jcs Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling
Chainu
Resolution9.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.-.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna u Q78 Y79 Y80 K81 N82 K83 T380 Q64 Y65 Y66 K67 N68 K69 T272
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0000055 ribosomal large subunit export from nucleus
GO:0006508 proteolysis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0030687 preribosome, large subunit precursor

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Cellular Component
External links
PDB RCSB:5jcs, PDBe:5jcs, PDBj:5jcs
PDBsum5jcs
PubMed26619264
UniProtQ03862|ARX1_YEAST Probable metalloprotease ARX1 (Gene Name=ARX1)

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