Structure of PDB 8pk0 Chain t

Receptor sequence
>8pk0t (length=325) Species: 9606 (Homo sapiens) [Search protein sequence]
IDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRK
RFVAGVGANSKISALKGSKGKDCEIPVPVGISVTDENGKIIGELNKENDR
ILVAQGGLGGKLLTNFLPLKGQKRIIHLDLKLIADVGLVGFPNAGKSSLL
SCVSHAKPAIELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHKFLKHIE
RTRQLLFVVDISGFQLSSHTQYRTAFETIILLTKELELYKEELQTKPALL
AVNKMDLPDAQDKFHELMSQLQNPKDFLHLFEKNMIPERTVEFQHIIPIS
AVTGEGIEELKNCIRKSLDEQANQE
3D structure
PDB8pk0 Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome.
Chaint
Resolution3.03 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna t I16 D17 K18 R20 S27 M30 Y32 P33 R52 K56 R61 K65 R66 N74 E101 L132 P133 K135 A171 L187 M191 I1 D2 K3 R5 S12 M15 Y17 P18 R37 K41 R46 K50 R51 N59 E86 L117 P118 K120 A156 L162 M166
BS02 GNP t N158 A159 G160 K161 S162 K279 A326 N143 A144 G145 K146 S147 K254 A301
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003723 RNA binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005739 mitochondrion

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8pk0, PDBe:8pk0, PDBj:8pk0
PDBsum8pk0
PubMed38042949
UniProtA4D1E9|GTPBA_HUMAN GTP-binding protein 10 (Gene Name=GTPBP10)

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