Structure of PDB 8cre Chain t

Receptor sequence

>8cret (length=200) Species: 5476 (Candida albicans) [Search protein sequence]

AISKNLPLLNNHFRKHWQERVRVHFDQAGKKASRRQSRLRKAAKIAPRPI
DALRPVVRAPTVKYNRKVRAGRGFTLAELKAVGIAPKYARTIGISVDHRR
QNKSQETFDANVARLQEYKSKLVIFDKKTKASEVASFEQVDVSATFPVEQ
PAPESGLRAVEVPEQTAYRTLRLARNEKKYKGIREKRAKEKAEAEAEKAK

3D structure

PDB

8cre Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement

Chain

Resolution

3.0 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	t	I3 K5 L7 L10 N11 N12 H13 F14 R15 K16 H17 W18 R23 F26 Q28 A29 K32 R35 R36 R39 R55 V58 R59 P61 T62 Y65 N66 K68 R70 G72 R73 L77 R91 D98 H99 R100 R101 S105 R170 R173 R176 N177 K179 K180 Y181 G183 R185	I2 K4 L6 L9 N10 N11 H12 F13 R14 K15 H16 W17 R22 F25 Q27 A28 K31 R34 R35 R38 R54 V57 R58 P60 T61 Y64 N65 K67 R69 G71 R72 L76 R90 D97 H98 R99 R100 S104 R169 R172 R175 N176 K178 K179 Y180 G182 R184
BS02	rna	t	F26 D27 G30	F25 D26 G29

External links

PDB	RCSB:8cre, PDBe:8cre, PDBj:8cre
PDBsum	8cre
PubMed
UniProt	A0A8H6F5V7

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