Structure of PDB 7z34 Chain t

Receptor sequence
>7z34t (length=731) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
KFKLPAEFITRPHPSKDHGKETCTAYIHPNVLSSLEINPGSFCTVGKIGE
NGILVIARAGDEEVHPVNVITLSTTIRSVGNLILGDRLELKKAQVQPPYA
TKVTVGSLQGYNILECMEEKVIQKLLDDSGVIMPGMIFQNLKTKAGDESI
DVVITDASDDNLFYLSPPFIFRKGSTHITFSKETQANRKYNLPEPLSYAA
VGGLDKEIESLKSAIEIPLHQPTLFSSFGVSPPRGILLHGPPGTGKTMLL
RVVANTSNAHVLTINGPSIVSKYLGETEAALRDIFNEARKYQPSIIFIDE
IDSIAPNRANDDSGEVESRVVATLLTLMDGMGAAGKVVVIAATNRPNSVD
PALRRPGRFDQEVEIGIPDVDARFDILTKQFSRMSSDRHVLDSEAIKYIA
SKTHGYVGADLTALCRESVMKTIQRGLGTDANIDKFSLKVTLKDVESAMV
DIRPSAMREIFLEMPKVYWSDIGGQEELKTKMKEMIQLPLEASETFARLG
ISAPKGVLLYGPPGCSKTLTAKALATESGINFLAVKGPEIFNKYVGESER
AIREIFRKARSAAPSIIFFDEIDALSPDRDGSSTSAANHVLTSLLNEIDG
VEELKGVVIVAATNRPDEIDAALLRPGRLDRHIYVGPPDVNARLEILKKC
TKKFNTEESGVDLHELADRTEGYSGAEVVLLCQEAGLAAIMEDLDVAKVE
LRHFEKAFKGIARGITPEMLSYYEEFALRSG
3D structure
PDB7z34 Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1.
Chaint
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.10: non-chaperonin molecular chaperone ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide t K318 Y319 L320 Y590 V591 K272 Y273 L274 Y544 V545
BS02 AGS t D645 R674 D599 R628
BS03 AGS t G519 G560 C561 S562 K563 L565 E617 N660 P684 I692 G721 V725 G473 G514 C515 S516 K517 L519 E571 N614 P638 I646 G675 V679
BS04 AGS t G289 A455 T458 G243 A409 T412
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0009410 response to xenobiotic stimulus
GO:0034214 protein hexamerization
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0030687 preribosome, large subunit precursor

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7z34, PDBe:7z34, PDBj:7z34
PDBsum7z34
PubMed36097293
UniProtP32794|AFG2_YEAST ATPase family gene 2 protein (Gene Name=AFG2)

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