Structure of PDB 7o9k Chain t

Receptor sequence
>7o9kt (length=381) Species: 9606 (Homo sapiens) [Search protein sequence]
KPHVNVGTIGHVDHGKTTLTAAITKILAEGGGAKFKKYEEIDNAPEERAR
GITINAAHVEYSTAARHYAHTDCPGHADYVKNMITGTAPLDGCILVVAAN
DGPMPQTREHLLLARQIGVEHVVVYVNKADEMVELVELEIRELLTEFGYK
GEETPVIVGSALCALEGRDPELGLKSVQKLLDAVDTYIPVPARDLEKPFL
LPVEAVYSVPGRGTVVTGTLERGILKKGDECELLGHSKNIRTVVTGIEMF
HKSLERAEAGDNLGALVRGLKREDLRRGLVMVKPGSIKPHQKVEAQVYIL
SKEEGGRHKPFVSHFMPVMFSLTWDMACRIILPPEKELAMPGEDLKFNLI
LRQPMILEKGQRFTLRDGNRTIGTGLVTNTL
3D structure
PDB7o9k Structural basis for late maturation steps of the human mitoribosomal large subunit.
Chaint
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna t K368 R429 K309 R370
BS02 GDP t V66 D67 G69 K70 T71 T72 K182 S219 A220 L221 V12 D13 G15 K16 T17 T18 K128 S160 A161 L162
BS03 MG t K70 T71 D126 K16 T17 D72
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
GO:0045471 response to ethanol
GO:0070125 mitochondrial translational elongation
Cellular Component
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0016020 membrane
GO:0042645 mitochondrial nucleoid
GO:0045202 synapse
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7o9k, PDBe:7o9k, PDBj:7o9k
PDBsum7o9k
PubMed34135318
UniProtP49411|EFTU_HUMAN Elongation factor Tu, mitochondrial (Gene Name=TUFM)

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