Structure of PDB 5yj0 Chain t

Receptor sequence
>5yj0t (length=98) Species: 10090 (Mus musculus) [Search protein sequence]
GPTSLCCKQCQETEITTKNEIFSLSLCGPMHETLTVYKASNLNLIGRPST
VHSWFPGYAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLP
3D structure
PDB5yj0 Structural basis of thalidomide enantiomer binding to cereblon
Chaint
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EF2 t H381 S382 W383 W389 W403 F405 H52 S53 W54 W60 W74 F76
BS02 ZN t C326 C329 C394 C397 C7 C10 C65 C68
External links
PDB RCSB:5yj0, PDBe:5yj0, PDBj:5yj0
PDBsum5yj0
PubMed29358579
UniProtQ8C7D2|CRBN_MOUSE Protein cereblon (Gene Name=Crbn)

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