Structure of PDB 8v87 Chain s

Receptor sequence

>8v87s (length=36) Species: 1247190 (Saccharomyces cerevisiae BY4741)

MRVRKRQSRRTSTKLKEGIKKKASAHRKKEKKMAKK

3D structure

• PDB: 8v87 The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
• Chain: s
• Resolution: 2.66 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	s	M1 R2 R4 R6 Q7 S8 R9 R10 S12 T13 K14 L15 E17 G18 I19 K21 K22 A23 S24 K29 K32	M1 R2 R4 R6 Q7 S8 R9 R10 S12 T13 K14 L15 E17 G18 I19 K21 K22 A23 S24 K29 K32

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003729 mRNA binding
• GO:0003924 GTPase activity
• GO:0005515 protein binding
• GO:0005525 GTP binding

Biological Process

• GO:0000055 ribosomal large subunit export from nucleus
• GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
• GO:0015031 protein transport
• GO:0042254 ribosome biogenesis

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0030687 preribosome, large subunit precursor

External links

• PDB: RCSB:8v87, PDBe:8v87, PDBj:8v87
• PDBsum: 8v87
• PubMed: 38632236
• UniProt: P40010|NUG1_YEAST Nuclear GTP-binding protein NUG1 (Gene Name=NUG1)