Structure of PDB 8pj1 Chain s

Receptor sequence
>8pj1s (length=159) Species: 9606 (Homo sapiens) [Search protein sequence]
TYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVNFTD
ICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRY
IKEYVTCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGK
RAQLRAKAN
3D structure
PDB8pj1 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining
Chains
Resolution3.4 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna s T322 R325 A326 R329 T148 R151 A152 R155
BS02 rna s T214 S249 I250 D251 K293 R296 K331 T40 S75 I76 D77 K119 R122 K157
BS03 ZN s C281 C284 C302 C107 C110 C128
BS04 GTP s T283 C305 S307 T109 C131 S133
External links
PDB RCSB:8pj1, PDBe:8pj1, PDBj:8pj1
PDBsum8pj1
PubMed
UniProtP20042|IF2B_HUMAN Eukaryotic translation initiation factor 2 subunit 2 (Gene Name=EIF2S2)

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