Structure of PDB 8etc Chain s

Receptor sequence

>8etcs (length=30) Species: 4896 (Schizosaccharomyces pombe)

VSLKKKSKRRTTRLRSRIEKKAAESKRKQK

3D structure

• PDB: 8etc Chromatin localization of nucleophosmin organizes ribosome biogenesis.
• Chain: s
• Resolution: 3.1 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	s	L4 K5 K6 S8 K9 R10 R11 T12 T13 R14 L15 R16 S17 I19 E20 K21 K22 E25 K27 R28 K29	L3 K4 K5 S7 K8 R9 R10 T11 T12 R13 L14 R15 S16 I18 E19 K20 K21 E24 K26 R27 K28

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003924 GTPase activity
• GO:0005525 GTP binding

Biological Process

• GO:0006364 rRNA processing
• GO:0015031 protein transport
• GO:0042254 ribosome biogenesis
• GO:1902626 assembly of large subunit precursor of preribosome

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus

External links

• PDB: RCSB:8etc, PDBe:8etc, PDBj:8etc
• PDBsum: 8etc
• PubMed: 36423630
• UniProt: O74791|GRN1_SCHPO GTPase grn1 (Gene Name=grn1)