Structure of PDB 7w1u Chain s

Receptor sequence
>7w1us (length=318) Species: 9823 (Sus scrofa) [Search protein sequence]
MFMINILSLIIPILLAVAFLTLVERKVLGYMQLRKGPNVVGPYGLLQPIA
DALKLFTKEPLRPATSSISMFIIAPILALSLALTMWVPLPMPYPLINMNL
GVLFMLAMSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIIL
LSVLLMNGSYTLSTLITTQEHIWMIFTSWPLAMMWFISTLAETNRAPFDL
TEGESELVSGFNVEYAAGPFAMFFMAEYANIIMMNAFTAILFLGASHDPH
TPELYTINFVLKTLALTITFLWIRASYPRFRYDQLMHLLWKSFLPLTLAL
CMWHISLPIMTASIPPQS
3D structure
PDB7w1u The coupling mechanism of mammalian mitochondrial complex I.
Chains
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UQ s L14 D51 A52 F224 M225 R274 L14 D51 A52 F224 M225 R274
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0009060 aerobic respiration
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0045271 respiratory chain complex I

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Cellular Component
External links
PDB RCSB:7w1u, PDBe:7w1u, PDBj:7w1u
PDBsum7w1u
PubMed35145322
UniProtO79874|NU1M_PIG NADH-ubiquinone oxidoreductase chain 1 (Gene Name=MT-ND1)

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