Structure of PDB 7a5k Chain r1

Receptor sequence
>7a5kr1 (length=696) Species: 9606 (Homo sapiens) [Search protein sequence]
PNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDS
MELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGA
VLVLCAVGGVQCQTMTVNRQMKRYNVPFLTFINKLDRMGSNPARALQQMR
SKLNHNAAFMQIPMGLEGNFKGIVDLIEERAIYFDGDFGQIVRYGEIPAE
LRAAATDHRQELIECVANSDEQLGEMFLEEKIPSISDLKLAIRRATLKRS
FTPVFLGSALKNKGVQPLLDAVLEYLPNPSEVQNYAILNKEDDSKEKTKI
LMNSSRDNSHPFVGLAFKLEVGRFGQLTYVRSYQGELKKGDTIYNTRTRK
KVRLQRLARMHADMMEDVEEVYAGDICALFGIDCASGDTFTDKANSGLSM
ESIHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENKET
VISGMGELHLEIYAQRLEREYGCPCITGKPKVAFRETITAPVPFDFTHKK
QSGGAGQYGKVIGVLEPLDPEDYTKLEFSDETFGSNIPKQFVPAVEKGFL
DACEKGPLSGHKLSGLRFVLQDGAHHMVDSNEISFIRAGEGALKQALANA
TLCILEPIMAVEVVAPNEFQGQVIAGINRRHGVITGQDGVEDYFTLYADV
PLNDMFGYSTELRSCTEGKGEYTMEYSRYQPCLPSTQEDVINKYLE
3D structure
PDB7a5k Elongational stalling activates mitoribosome-associated quality control.
Chainr1
Resolution3.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna r1 I55 D56 R98 H124 Q152 R178 Q661 A666 N669 R670 Q678 R704 E708 I14 D15 R57 H83 Q111 R137 Q620 A625 N628 R629 Q637 R663 E667
BS02 rna r1 R364 F365 Q396 K541 F574 N577 N622 R323 F324 Q355 K500 F533 N536 N581
BS03 MG r1 T60 K80 T101 T19 K39 T60
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
GO:0070125 mitochondrial translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7a5k, PDBe:7a5k, PDBj:7a5k
PDBsum7a5k
PubMed33243891
UniProtQ96RP9|EFGM_HUMAN Elongation factor G, mitochondrial (Gene Name=GFM1)

[Back to BioLiP]