Structure of PDB 8c3a Chain r

Receptor sequence

>8c3ar (length=208) Species: 5476 (Candida albicans) [Search protein sequence]

ARRPARCYRYCKNKPYPKSRYNRAVPDAKIRIYDLGRKKATVDEFPLCIH
LVSNELEQLSSEALEAARICANKYITKVSGRDSFHLRVRVHPFHVLRINK
MQGMRGAWGKPHGLAARVSIGQIIMSARTKDSNKDVVIEGLRRARYKFPG
QQKIIISKKWGFTPLNRDEYIAKKTNGEVIDDGAYVKFLSRKGNLEANLQ
QFPNYQYS

3D structure

PDB

8c3a New crystal system to promote screening for new eukaryotic inhibitors

Chain

Resolution

3.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	r	R3 R4 A6 R7 K13 N14 K15 P16 Y17 Y22 Y34 D35 K39 S61 E63 A64 A67 R90 H92 F94 R98 N100 M115 R116 W119 Q133 R154 Y157 K158 P160 D193 G194 A195 Y196 K198	R2 R3 A5 R6 K12 N13 K14 P15 Y16 Y21 Y33 D34 K38 S60 E62 A63 A66 R89 H91 F93 R97 N99 M104 R105 W108 Q122 R143 Y146 K147 P149 D182 G183 A184 Y185 K187
BS02	rna	r	Y11 E56 L57 I131 S201 R202 K203 G204 L206	Y10 E55 L56 I120 S190 R191 K192 G193 L195
BS03	MG	r	F159 G161	F148 G150
BS04	MG	r	K30 E63	K29 E62

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0009986	cell surface
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8c3a, PDBe:8c3a, PDBj:8c3a
PDBsum	8c3a
PubMed
UniProt	Q5AIB8\|RL10_CANAL Large ribosomal subunit protein uL16 (Gene Name=RPL10)

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