Structure of PDB 8v84 Chain q

Receptor sequence
>8v84q (length=358) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence]
NLTSTRTRMIEIVKVLENFKTLGAEGRSRGEYVDRLLKDICEYFGYTPFL
AEKLFNLFSPAEAMEFFEANEIARPITIRTNTLKTRRRDLAQTLVNRGVN
LQPIGSWTKVGLQIFDSQVPIGATPEYLAGHYILQAASSFLPVIALDPHE
NERILDMAAAPGGKTTYISAMMKNTGCVFANDANKSRTKSLIANIHRLGC
TNTIVCNYDAREFPKVIGGFDRILLDAPCSGTGVIGKDQSVKVSRTEKDF
IQIPHLQKQLLLSAIDSVDCNSKHGGVIVYSTCSVAVEEDEAVIDYALRK
RPNVKLVDTGLAIGKEAFTSYRGKKFHPSVKLARRYYPHTYNVDGFFVAK
FQKIGPSS
3D structure
PDB8v84 The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Chainq
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.310: 25S rRNA (cytosine(2870)-C(5))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna q K215 R224 R348 K410 G413 D464 F513 S515 R517 G518 K520 K20 R29 R153 K215 G218 D269 F318 S320 R322 G323 K325
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008173 RNA methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000470 maturation of LSU-rRNA
GO:0001510 RNA methylation
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0031167 rRNA methylation
GO:0032259 methylation
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:0070475 rRNA base methylation
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8v84, PDBe:8v84, PDBj:8v84
PDBsum8v84
PubMed38632236
UniProtP40991|NOP2_YEAST 25S rRNA (cytosine(2870)-C(5))-methyltransferase (Gene Name=NOP2)

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