Structure of PDB 8cqw Chain q

Receptor sequence

>8cqwq (length=189) Species: 5476 (Candida albicans) [Search protein sequence]

MKYIQTDQILDIPEGVTVDIKARVVKVTGPRGELTKDLKHIDVTFNKINN
RAIKITVHNGDRKHVAALRTVKSLIANLITGVTKGYKYKMRFVYAHFPIN
VNIIKKDGQDYVEIRNFLGEKRVREVKIHEGVTMEISSTQKDELIVSGNS
LEAVSQNAADIQQICRVRNKDIRKFLDGIYVSERGTIVE

3D structure

PDB

8cqw Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement

Chain

Resolution

3.05 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	q	M1 R23 H40 D42 V43 T44 H58 R62 A66 R69 T70 S73 H96 F97 E120 K121 R122 S155 Q156 Q163 R166 R168 K170 D171 R173 K174 F175	M1 R23 H40 D42 V43 T44 H58 R62 A66 R69 T70 S73 H96 F97 E120 K121 R122 S155 Q156 Q163 R166 R168 K170 D171 R173 K174 F175

External links

PDB	RCSB:8cqw, PDBe:8cqw, PDBj:8cqw
PDBsum	8cqw
PubMed
UniProt	A0A8H6C3N3

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