Structure of PDB 7ui9 Chain q

Receptor sequence
>7ui9q (length=515) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
PHEIYGSMPLEQLIPIILRQRGPGFKFVDLNEKELQNEIKQLGSQEQFVK
RRRDMLEHINLAMNESSLALEFVSLLLSSVKESTGMSSMSPFLRKVVKPS
SLNSDKIPYVAPTKKEYIELDILNKGWKLQSLNESKDLLRASFNKLSSIL
QNEHDYWNKIMQSISNKDVIFKIRDRTSGQKLLAIKYGYEDSGSTYKHDR
GIANIRNNIESQNLDLIPHSSSVFKGTDFVHSVKKFLRVRIFTKIESEDD
YILSGESVMDRDSESEEAETKDIRKQIQLLKKIIFEKELMYQIKKECALL
ISYGVSIENENKVIIELPNEKFEIELLSLDLPKINDKRANLMLVMLRLLL
VVIFKKTLRSRISSPHGLINLNVDDDILIIRPILGKVRFANYKLLLKKII
KDYVLDIVPGSSITETEVEDDENITKLNKEIRAFDKLLNIPRRELKINLP
LTEHKSPNLSLMLESPNYCNALIHIKFSAGTEANAVSFDTTFSDFKEVED
FLHFIVAEYIQQKKV
3D structure
PDB7ui9 Structural basis of a transcription pre-initiation complex on a divergent promoter.
Chainq
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide q N216 S219 E223 S242 F244 L245 N64 S67 E71 S90 F92 L93
Gene Ontology
Molecular Function
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
GO:0001139 RNA polymerase II complex recruiting activity
GO:0003712 transcription coregulator activity
GO:0005515 protein binding
GO:0140297 DNA-binding transcription factor binding
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006367 transcription initiation at RNA polymerase II promoter
GO:0032968 positive regulation of transcription elongation by RNA polymerase II
GO:0034605 cellular response to heat
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051123 RNA polymerase II preinitiation complex assembly
GO:0060261 positive regulation of transcription initiation by RNA polymerase II
Cellular Component
GO:0005634 nucleus
GO:0016592 mediator complex
GO:0070847 core mediator complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ui9, PDBe:7ui9, PDBj:7ui9
PDBsum7ui9
PubMed36731470
UniProtP32569|MED17_YEAST Mediator of RNA polymerase II transcription subunit 17 (Gene Name=SRB4)

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