Structure of PDB 6olf Chain q

Receptor sequence
>6olfq (length=91) Species: 9606 (Homo sapiens) [Search protein sequence]
AKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRA
VGIWHCGSCMKTVAGGAWTYNTTSAVTVKSAIRRLKELKDQ
3D structure
PDB6olf Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Chainq
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna q A2 R4 T5 V8 G9 I10 G12 K13 G15 T16 R17 Y18 G19 A20 S21 R23 H34 C42 K44 K46 R49 A51 G58 W69 A1 R3 T4 V7 G8 I9 G11 K12 G14 T15 R16 Y17 G18 A19 S20 R22 H33 C41 K43 K45 R48 A50 G57 W68
BS02 ZN q C39 C57 C38 C56
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:6olf, PDBe:6olf, PDBj:6olf
PDBsum6olf
PubMed31160784
UniProtP61513|RL37A_HUMAN Large ribosomal subunit protein eL43 (Gene Name=RPL37A)

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