Structure of PDB 6z3m Chain p

Receptor sequence
>6z3mp (length=158) Species: 9606 (Homo sapiens) [Search protein sequence]
PSYLFCGLFGPHLRTFKDNFQTCKVEGAWPLIDNNYLSVQVTNVPVVPGS
SATATNKITIIFKAHHGCTDQKVYQAVTDDLPAAFVDGTTSGGDSDAKSL
RIVEYVEMHARYIGTTVFVRQVGRYLTLAIRMPEDLAMSYEESQDLQLCV
NGCPLSER
3D structure
PDB6z3m Repulsive guidance molecules lock growth differentiation factor 5 in an inhibitory complex.
Chainp
Resolution5.501 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide p G225 C226 R274 Y275 G277 P296 D298 L299 G67 C68 R111 Y112 G114 P133 D135 L136
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0015026 coreceptor activity
GO:0042802 identical protein binding
Biological Process
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0030509 BMP signaling pathway
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005886 plasma membrane
GO:0045121 membrane raft
GO:0098552 side of membrane

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Molecular Function

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Cellular Component
External links
PDB RCSB:6z3m, PDBe:6z3m, PDBj:6z3m
PDBsum6z3m
PubMed32576689
UniProtQ6NW40|RGMB_HUMAN Repulsive guidance molecule B (Gene Name=RGMB)

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