Structure of PDB 6fyx Chain p

Receptor sequence
>6fyxp (length=647) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
EFNFDQYIVVNGAPVIPSAKVPVLKKALTSLFSKAGKVVNMEFPIDEATG
KTKGFLFVECGSMNDAKKIIKSFHGKRLDLKHRLFLYTMKDVERYNSPSS
SLKSWLMDDKVRDQFVLQDDVKTSVFWNSMFNEEDSLVESRENWSTNYVR
FSPKGTYLFSYHQQGVTAWGGPNFDRLRRFYHPDVRNSSVSPNEKYLVTF
STEPIIVEEDNEFSPFTKKNEGHQLCIWDIASGLLMATFPVIKSPYLKWP
LVRWSYNDKYCARMVGDSLIVHDATKNFMPLEAKALKPSGIRDFSFAPEG
VKLQPFRNGDEPSVLLAYWTPETNNSACTATIAEVPRGRVLKTVNLVQVS
NVTLHWQNQAEFLCFNVERHTKSGKTQFSNLQICRLTERDIPVEKVELKD
SVFEFGWEPHGNRFVTISVHEVADMNYAIPANTIRFYAPETKEKTDVIKR
WSLVKEIPKTFANTVSWSPAGRFVVVGALVGPNMRRSDLQFYDMDYPGEK
NINDNNDVSASLKDVAHPTYSAATNITWDPSGRYVTAWSSSLKHKVEHGY
KIFNIAGNLVKEDIIAGFKNFAWRPRPSILSNAERKKVRKNLREWSAQFE
EQDAMEADTAMRDLHQRELLKQWTEYREKIGQEMEKSMNFKIFDVQP
3D structure
PDB6fyx Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Chainp
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna p N412 T458 K459 S460 K462 T463 N325 T371 K372 S373 K375 T376
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0031369 translation initiation factor binding
GO:0042802 identical protein binding
Biological Process
GO:0001732 formation of cytoplasmic translation initiation complex
GO:0002183 cytoplasmic translational initiation
GO:0006412 translation
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005852 eukaryotic translation initiation factor 3 complex
GO:0010494 cytoplasmic stress granule
GO:0016282 eukaryotic 43S preinitiation complex
GO:0033290 eukaryotic 48S preinitiation complex
GO:0043614 multi-eIF complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6fyx, PDBe:6fyx, PDBj:6fyx
PDBsum6fyx
PubMed30475211
UniProtP06103|EIF3B_YEAST Eukaryotic translation initiation factor 3 subunit B (Gene Name=PRT1)

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