Structure of PDB 8bhf Chain n1

Receptor sequence
>8bhfn1 (length=236) Species: 9606 (Homo sapiens) [Search protein sequence]
MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKK
EIKKLQRLRDQIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKT
KAYSKEGLGLAQKVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLS
VQTRKKKGDKDKQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAI
RKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQ
3D structure
PDB8bhf Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Chainn1
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna n1 Q56 R59 K63 E85 K92 E95 K99 K101 Y103 S104 K105 Q56 R59 K63 E85 K92 E95 K99 K101 Y103 S104 K105
BS02 rna n1 M1 A2 R5 K16 K53 K54 R57 M1 A2 R5 K16 K53 K54 R57
BS03 rna n1 N39 Q40 K43 Y103 N39 Q40 K43 Y103
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus
GO:0030015 CCR4-NOT core complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8bhf, PDBe:8bhf, PDBj:8bhf
PDBsum8bhf
PubMed37653241
UniProtB7Z6J7

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