Structure of PDB 8v83 Chain n

Receptor sequence
>8v83n (length=337) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence]
FITRSQAVRKLQVSLADFRRLCIFKGIYPFYYAKDIQYLMHEPVLAKFRE
HKTFARKLTRALGRGEVSSAKRLEENRDSYTLDHIIKERYPSFPDAIRDI
DDALNMLFLFSNLPSTNQVSSKIINDAQKICNQWLAYVAKERLVRKVFVS
IKGVYYQANIKGEEVRWLVPFKFPENIPSDVDFRIMLTFLEFYSTLLHFV
LYKLYTDSGLIYPPKLDLKKDKIISGLSSYILESRKYDSPVASLFSAFVF
YVSREVPIDILEFLILSCGGNVISEAAMDQISKVTHQIVDRPVLKNKVAG
RTYIQPQWIFDCINKGELVPANKYLPGEALPPHLSPW
3D structure
PDB8v83 The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Chainn
Resolution2.53 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna n K89 T91 R92 R104 K57 T59 R60 R72
BS02 rna n Q69 H73 K84 R88 Q37 H41 K52 R56
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor
GO:0070545 PeBoW complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8v83, PDBe:8v83, PDBj:8v83
PDBsum8v83
PubMed38632236
UniProtP53261|PESC_YEAST Pescadillo homolog (Gene Name=NOP7)

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