Structure of PDB 8eti Chain n

Receptor sequence
>8etin (length=369) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence]
QKGKAGAARIYITRNQALKKLQLTLADFRRICILKGVYPREPKNKKKANK
GSTAPVTFYYTKDIQYLLHEPIVQKFREYKVFARKLSKALGKGELETAKR
LEARKPTYSLDHIIKERYPTFHDALKDIDDALSMLFLFSTMPVTDKIGAA
TVANCERLCAEFQHYVIRSNSLRKAFLSIKGIYYQAEIFGEQITWIVPYK
FAQSVPTDVDFRIMHTFLEFYQALMGFVNFKLYNTLGLRYPPKIDVAKSE
SAAGLAAYELEESNTSLFSNFTFFLSREVPRFSLEFVIRAFGGKVGWDPI
LGSGSPFSESDPVITHHICDRPHISQKYEGRIYIQPQWVYDSINKGILER
TDLYACGATLPPHLSPFVK
3D structure
PDB8eti Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Chainn
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna n K90 K93 K85 K88
BS02 rna n A10 G11 R14 I15 K48 Q70 H74 V86 A5 G6 R9 I10 K43 Q65 H69 V81
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor
GO:0070545 PeBoW complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8eti, PDBe:8eti, PDBj:8eti
PDBsum8eti
PubMed36423630
UniProtO60164|PESC_SCHPO Pescadillo homolog (Gene Name=ppp1)

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