Structure of PDB 7r45 Chain n

Receptor sequence
>7r45n (length=171) Species: 9913 (Bos taurus) [Search protein sequence]
YLTHQQKVLRLYKRALRHLESWCIHRDKYRYFACLLRARFDEHKNEKDMV
KATQLLREAEEEFWHGQHPQPYIFPESPGGTSYERYECYKVPEWCLDDWH
PSEKAMYPDYFAKREQWKKLRRESWEREVKQLQEETPVGGPRTEALPPAR
KQGDLPPLWWHIVTRPRERPM
3D structure
PDB7r45 Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Chainn
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EHZ n H11 Q12 V15 L26 R46 F47 H50 K51 E53 E69 F70 H4 Q5 V8 L19 R39 F40 H43 K44 E46 E62 F63
Gene Ontology
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0032981 mitochondrial respiratory chain complex I assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

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Biological Process
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Cellular Component
External links
PDB RCSB:7r45, PDBe:7r45, PDBj:7r45
PDBsum7r45
PubMed36701435
UniProtQ02369|NDUB9_BOVIN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (Gene Name=NDUFB9)

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