Structure of PDB 7ase Chain n

Receptor sequence
>7asen (length=225) Species: 5693 (Trypanosoma cruzi) [Search protein sequence]
SNDLYALLKRITRQEVERRMIEHEQLRQKQQRVPQVERFLDATSKTGSSG
SSGGGGNKATEEGCGYNYSVMLRRLFFALNRNKESSAMTERNRLPEPKLE
KIGKKKVIITNFGRICQAFNRPIQDVKDYIEKELSVGGNLDSNDALILKY
EIQKSTAFDNILYKYLDEFVKCNSCHKIDTTLTKEGRRMELRCNWCTATR
TVQAVGSATYSAQVGKRSKARLQAM
3D structure
PDB7ase Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts.
Chainn
Resolution3.33 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna n G219 N255 D257 R303 G103 N139 D141 R187
BS02 rna n Q329 R333 Q213 R217
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003743 translation initiation factor activity
GO:0031369 translation initiation factor binding
Biological Process
GO:0001731 formation of translation preinitiation complex
GO:0001732 formation of cytoplasmic translation initiation complex
GO:0006412 translation
GO:0006413 translational initiation
Cellular Component
GO:0005850 eukaryotic translation initiation factor 2 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ase, PDBe:7ase, PDBj:7ase
PDBsum7ase
PubMed33357443
UniProtQ4DH88

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