Structure of PDB 7nad Chain m

Receptor sequence

>7nadm (length=412) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence]

DHVMHLRAPKLPLDLYLAPRVRKNKLNIDPNSLIPELPSPKDLRPFPIRC
STIYAGHKGKVRTLSIDPSGLWLATGSDDGTVRVWEILTGREVYRTTLID
NPDYHIECIEWNPDANNGILAVAVGENIHLIVPPIFGYDIENNGKTKIED
GFGYDTFGTVKKSNLEVNAKNAVKKQVAQWNKPSQKQLEKDICITISCKK
TVKKLSWHRKGDYFVTVQPDSGNTSVLIHQVSKHLTQSPFKKSKGIIMDA
KFHPFKPQLFVCSQRYVRIYDLSQQILVKKLLPGARWLSKIDIHPRGDNL
IASSFDKRVLWHDLDLASTPYKTLRYHEKAVRSVNFHKKLPLFSSAADDG
TIHVFHATVYDDMMKNPMIVPLKKLTGHKVINSLGVLDAIWHPREAWLFS
AGADNTARLWTT

3D structure

PDB

7nad Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.

Chain

Resolution

3.04 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	m	L392 K404 L405 I407 F534 G535 Y536 D537 T538 F539 G617 N618 K639 Q659 R660 Y661 L677 R681 W682 D701 K702 R703 T714 R720	L13 K25 L26 I28 F152 G153 Y154 D155 T156 F157 G222 N223 K244 Q264 R265 Y266 L282 R286 W287 D306 K307 R308 T319 R325
BS02	peptide	m	R325 P327 L392 D393 P398 R399 V400 K402 N403 K404 L405 N406 I407	R7 P9 L13 D14 P19 R20 V21 K23 N24 K25 L26 N27 I28

Gene Ontology

	Biological Process
GO:0006364	rRNA processing
GO:0042254	ribosome biogenesis

View graph for
Biological Process

External links

PDB	RCSB:7nad, PDBe:7nad, PDBj:7nad
PDBsum	7nad
PubMed	36482249
UniProt	Q04660\|ERB1_YEAST Ribosome biogenesis protein ERB1 (Gene Name=ERB1)

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