Structure of PDB 6zu9 Chain m

Receptor sequence
>6zu9m (length=147) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
INICRDNHDPFYRYKMPPIQAKVEGRGNGIKTAVLNVADISHALNRPAPY
IVKYFGFELGAQTSISVDKDRYLVNGVHEPAKLQDVLDGFINKFVLCGSC
KNPETEIIITKDNDLVRDCKACGKRTPMDLRHKLSSFILKNPPDSVS
3D structure
PDB6zu9 A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Chainm
Resolution6.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna m G58 F59 E60 L61 G62 A63 Q64 N77 G78 S138 G56 F57 E58 L59 G60 A61 Q62 N75 G76 S136
BS02 rna m G29 G31 G27 G29
Gene Ontology
Molecular Function
GO:0003743 translation initiation factor activity
GO:0005092 GDP-dissociation inhibitor activity
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0008270 zinc ion binding
GO:0031369 translation initiation factor binding
GO:0071074 eukaryotic initiation factor eIF2 binding
Biological Process
GO:0001732 formation of cytoplasmic translation initiation complex
GO:0006412 translation
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
GO:0042256 cytosolic ribosome assembly
GO:0045947 negative regulation of translational initiation
Cellular Component
GO:0005829 cytosol
GO:0033290 eukaryotic 48S preinitiation complex
GO:0043614 multi-eIF complex

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Cellular Component
External links
PDB RCSB:6zu9, PDBe:6zu9, PDBj:6zu9
PDBsum6zu9
PubMed33289941
UniProtP38431|IF5_YEAST Eukaryotic translation initiation factor 5 (Gene Name=TIF5)

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