Structure of PDB 4pjo Chain m

Receptor sequence

>4pjom (length=50) Species: 9606 (Homo sapiens)

PKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLID

3D structure

• PDB: 4pjo ?
• Chain: m
• Resolution: 3.3 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	m	T14 H15 S17 S19 V20	T13 H14 S16 S18 V19
BS02	rna	m	T11 Y12 T14 H24 R28	T10 Y11 T13 H23 R27
BS03	ZN	m	C6 H24 H30	C5 H23 H29
BS04	MG	m	G27 H30	G26 H29

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0008270 zinc ion binding

Biological Process

• GO:0000387 spliceosomal snRNP assembly
• GO:0000398 mRNA splicing, via spliceosome

Cellular Component

• GO:0005634 nucleus
• GO:0005685 U1 snRNP

External links

• PDB: RCSB:4pjo, PDBe:4pjo, PDBj:4pjo
• PDBsum: 4pjo
• PubMed: 25555158
• UniProt: P09234|RU1C_HUMAN U1 small nuclear ribonucleoprotein C (Gene Name=SNRPC)