Structure of PDB 5obm Chain l6

Receptor sequence

>5obml6 (length=157) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

SAQKAPKWYPSEDVAALKKTRKAARPQKLRASLVPGTVLILLAGRFRGKR
VVYLKHLEDNTLLISGPFKVNGVPLRRVNARYVIATSTKVSVEGVNVEKF
NVEYFAKEKEIKAERVEDQKVVDKALIAEIKKTPLLKQYLSASFSLKNGD
KPHMLKF

3D structure

PDB

5obm Aminoglycoside interactions and impacts on the eukaryotic ribosome.

Chain

Resolution

3.4 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	l6	S2 A3 K5 W9 A17 L18 K19 K20 T21 R22 K23 A24 R26 Q28 G45 R46 R48 N61 T62 F69 K70 V71 N72 G73 P75 R77 R78 V79 N80 R82 Y83 K108 I130 V135 Q157 A161 S162 K166 N167	S1 A2 K4 W8 A16 L17 K18 K19 T20 R21 K22 A23 R25 Q27 G44 R45 R47 N60 T61 F68 K69 V70 N71 G72 P74 R76 R77 V78 N79 R81 Y82 K107 I111 V116 Q138 A142 S143 K147 N148

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:5obm, PDBe:5obm, PDBj:5obm
PDBsum	5obm
PubMed	29208708
UniProt	Q02326\|RL6A_YEAST Large ribosomal subunit protein eL6A (Gene Name=RPL6A)

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