Structure of PDB 8ixg Chain l

Receptor sequence
>8ixgl (length=325) Species: 9606 (Homo sapiens) [Search protein sequence]
AECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQS
STSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEG
MGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLS
VHEDKNRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRS
HSIFLINVKQENTQTEQKLSGKLYLVDLAGSAKVSKTGAEGAVLDEAKNI
NKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSP
SSYNESETKSTLLFGQRAKTIKNTV
3D structure
PDB8ixg Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Chainl
Resolution4.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP l R16 P17 Q86 T87 S88 S89 G90 K91 T92 H93 N198 S202 R203 G234 R12 P13 Q82 T83 S84 S85 G86 K87 T88 H89 N194 S198 R199 G230
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:8ixg, PDBe:8ixg, PDBj:8ixg
PDBsum8ixg
PubMed37439022
UniProtP33176|KINH_HUMAN Kinesin-1 heavy chain (Gene Name=KIF5B)

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