Structure of PDB 7w0h Chain l

Receptor sequence
>7w0hl (length=603) Species: 9823 (Sus scrofa) [Search protein sequence]
MNPFASLTLTTLTILTIPIMMSNSNIYKTNLYPNYVKTTVSYAFTLSLVP
LLMFMHTGQEMIISNWHWMTLQTVELSLSFKMDYFSVMFIPVALFVTWSI
MEFSMWYMHSDPFINRFFKYLLLFLITMMILVTANNLFQLFIGWEGVGIM
SFLLIGWWHGRTDANTAALQAILYNRIGDIGFVLSMAWFLTHSNAWDLQQ
IFMLNNECPNMPLIGLLLAAAGKSAQFGLHPWLPSAMEGPTPVSALLHSS
TMVVAGVFLLIRFYPLMETNKLVQTMTLCLGAITTLFTALCAITQNDIKK
IVAFSTSSQLGLMMVTIGINQPHLAFLHICMHAFFKAMLFMCSGSIIHSL
NDEQDIRKMGGLYKAMPFTTTALIIGSLALTGMPYLTGFYSKDLIIEAVN
MSYTNAWALLMTLIATSLTAAYSTRIIFFAFLGKPRFPPLVLINENNPLL
INSIKRLLIGSIFAGFIISNNIPPMTVPNTTMPLYMKMTALIVTIMGFML
ALELNNTTYYLKFKYPSQTYKFSNMLGYYPSIMHRLPTYHNLSMSQKSAS
SLLDLIWLETILPKTTSFIQMKMSIMVSNQKGLIKLYFLSFLITIMISMT
LFN
3D structure
PDB7w0h The coupling mechanism of mammalian mitochondrial complex I.
Chainl
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLX l N23 W66 N23 W66
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0015990 electron transport coupled proton transport
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0042773 ATP synthesis coupled electron transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7w0h, PDBe:7w0h, PDBj:7w0h
PDBsum7w0h
PubMed35145322
UniProtQ9TDR1|NU5M_PIG NADH-ubiquinone oxidoreductase chain 5 (Gene Name=MT-ND5)

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