Structure of PDB 7otc Chain l

Receptor sequence

>7otcl (length=123) Species: 469008 (Escherichia coli BL21(DE3)) [Search protein sequence]

ATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRK
VCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGA
LDCSGVKDRKQARSKYGVKRPKA

3D structure

PDB

7otc The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.

Chain

Resolution

2.9 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	l	N5 Q6 L7 R9 R12 A13 R14 K15 K18 A26 C27 P28 Q29 R31 K43 K44 N46 S47 A48 L49 R50 K51 T58 Y66 G68 G69 E70 R83 G84 K88 X89 P91 R110 K111 Q112 A113 R114 S115 K116 G118 V119 K120 R121	N4 Q5 L6 R8 R11 A12 R13 K14 K17 A25 C26 P27 Q28 R30 K42 K43 N45 S46 A47 L48 R49 K50 T57 Y65 G67 G68 E69 R82 G83 K87 X88 P90 R109 K110 Q111 A112 R113 S114 K115 G117 V118 K119 R120

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

External links