Structure of PDB 6kva Chain l

Receptor sequence

>6kval (length=217) Species: 9606 (Homo sapiens) [Search protein sequence]

VLTQPSSLSASPGASVSLTCTLRSGINVGAYRIYWYQQKPGSPPQFLLRY
KSDSDKQQGSGVPSRFSGSRDASANAGILLISGLRSEDEADYYCAIWHSS
AWVFGGGTQLTVLGGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPG
AVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYS
CQVTHEGSTVEKTVAPT

3D structure

PDB

6kva Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms.

Chain

Resolution

2.2 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	l	Y36 Y38 F48 R51 W99 W104	Y34 Y36 F46 R49 W97 W102

External links

PDB	RCSB:6kva, PDBe:6kva, PDBj:6kva
PDBsum	6kva
PubMed	33953162

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