Structure of PDB 8s8j Chain k

Receptor sequence
>8s8jk (length=470) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
GETEEEKRKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIG
HVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPE
PDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSG
AAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREE
SALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPR
DFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRP
GIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLC
RADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLE
PNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIEK
HWRLIGWATIKKGTTLEPIA
3D structure
PDB8s8j Structural basis of AUC codon discrimination during translation initiation in yeast.
Chaink
Resolution4.7 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna k F321 D322 V323 N324 K325 P326 K334 R408 F264 D265 V266 N267 K268 P269 K277 R351
BS02 peptide k Q248 V251 D252 Q263 I280 P282 S284 Y289 N290 A293 Q191 V194 D195 Q206 I223 P225 S227 Y232 N233 A236
BS03 MET k Y142 R319 F321 F381 Y85 R262 F264 F324
External links
PDB RCSB:8s8j, PDBe:8s8j, PDBj:8s8j
PDBsum8s8j
PubMed39193907
UniProtP32481|IF2G_YEAST Eukaryotic translation initiation factor 2 subunit gamma (Gene Name=GCD11)

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