Structure of PDB 8s8g Chain k

Receptor sequence

>8s8gk (length=470) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

GETEEEKRKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIG
HVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPE
PDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSG
AAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREE
SALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPR
DFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRP
GIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLC
RADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLE
PNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIEK
HWRLIGWATIKKGTTLEPIA

3D structure

PDB

8s8g Structural basis of AUC codon discrimination during translation initiation in yeast.

Chain

Resolution

4.0 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	k	K129 D322 V323 N324 P326 K334 V337 S379	K72 D265 V266 N267 P269 K277 V280 S322
BS02	MET	k	Y142 R319 F381 A382 L395 G397	Y85 R262 F324 A325 L338 G340

External links

PDB	RCSB:8s8g, PDBe:8s8g, PDBj:8s8g
PDBsum	8s8g
PubMed	39193907
UniProt	P32481\|IF2G_YEAST Eukaryotic translation initiation factor 2 subunit gamma (Gene Name=GCD11)

[Back to BioLiP]