Structure of PDB 7zyj Chain k

Receptor sequence
>7zyjk (length=206) Species: 5689 (Leishmania tarentolae) [Search protein sequence]
MAETAIAFRCKDYVMVAAAGLNAFYYIKITDAEDKITQLDTHQLVACTGE
NGPRVNFTEYIKCNLALNRMRQHGRHSSCESTANFMRNCLASAIRSREGA
YQVNCLFAGYDTPVSEDDDGVVGPQLFYMDYLGTLQAVPYGCHGYGACFV
TALLDRLWRPDLSQQEGLELMQKCCDEVKRRVIISNSYFFVKAVTKNGVE
VITAVH
3D structure
PDB7zyj Discovery of Novel Quinoline-Based Proteasome Inhibitors for Human African Trypanosomiasis (HAT).
Chaink
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 KFC k F24 Y26 I29 F24 Y26 I29
Gene Ontology
Biological Process
GO:0010498 proteasomal protein catabolic process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005839 proteasome core complex
GO:0019774 proteasome core complex, beta-subunit complex

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Biological Process

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Cellular Component
External links
PDB RCSB:7zyj, PDBe:7zyj, PDBj:7zyj
PDBsum7zyj
PubMed35993839
UniProtA0A640KTY7

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