Structure of PDB 7c0m Chain k

Receptor sequence
>7c0mk (length=366) Species: 9606 (Homo sapiens) [Search protein sequence]
DAAPGASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGV
GLLNTGSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRN
PKENPLSQFLEGEILSASKMLSKFRKIIKEEINDIKDTDVIMKRKRGGSP
AVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKP
FYLVPKHAKEGNGFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCR
KDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWD
RKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTK
QIEYERNNEFPVFDEF
3D structure
PDB7c0m Structural basis for the inhibition of cGAS by nucleosomes.
Chaink
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.86: cyclic GMP-AMP synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN k H390 C396 C397 H234 C240 C241
External links
PDB RCSB:7c0m, PDBe:7c0m, PDBj:7c0m
PDBsum7c0m
PubMed32912999
UniProtQ8N884|CGAS_HUMAN Cyclic GMP-AMP synthase (Gene Name=CGAS)

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