Structure of PDB 3jah Chain jj

Receptor sequence

>3jahjj (length=576) Species: 9986 (Oryctolagus cuniculus)

KLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISET
LCIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPG
EVLGLVGTNGIGKSTALKILAGKQKPNLGKYDWQEILTYFRGSELQNYFT
KILEDDLKAIIKPQYVDQIPKAAKGTVGSILDRKDETKTQAIVCQQLDLT
HLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAI
TIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVRE
GINIFLDGYVPTENLRFRDASLVFMCMYKYPGMKKKMGEFELAIVAGEFT
DSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKS
TGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRV
ALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEH
DFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDP
NNYRPRINKLNSIKDVEQKKSGNYFF

3D structure

• PDB: 3jah Structural basis for stop codon recognition in eukaryotes.
• Chain: jj
• Resolution: 3.45 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	jj	T443 R506	T423 R486
BS02	rna	jj	R148 G149 S150 Q153 S304 R567 K579 I583 K584	R141 G142 S143 Q146 S297 R547 K559 I563 K564
BS03	SF4	jj	C29 V31 C38 I39 C55 I56 C58 G59 C61	C26 V28 C35 I36 C52 I53 C55 G56 C58
BS04	SF4	jj	C16 K17 C21 Q23 C25 A48 C65 P66 F67	C13 K14 C18 Q20 C22 A45 C62 P63 F64
BS05	ADP	jj	G113 G115 K116 S117 T118	G110 G112 K113 S114 T115

Gene Ontology

Molecular Function

• GO:0005506 iron ion binding
• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity
• GO:0043024 ribosomal small subunit binding

Biological Process

• GO:0000054 ribosomal subunit export from nucleus
• GO:0006413 translational initiation
• GO:0006415 translational termination

External links

• PDB: RCSB:3jah, PDBe:3jah, PDBj:3jah
• PDBsum: 3jah
• PubMed: 26245381
• UniProt: G1SG72