Structure of PDB 3jag Chain jj

Receptor sequence

>3jagjj (length=577) Species: 9986 (Oryctolagus cuniculus)

KLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISET
LCIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPG
EVLGLVGTNGIGKSTALKILAGKQKPNLGKYDWQEILTYFRGSELQNYFT
KILEDDLKAIIKPQYVDQIPKAAKGTVGSILDRKDETKTQAIVCQQLDLT
HLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAI
TIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVRE
GINIFLDGYVPTENLRFRDASLVFMCMYKYPGMKKKMGEFELAIVAGEFT
DSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKS
TGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRV
ALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEH
DFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDP
NNYRPRINKLNSIKDVEQKKSGNYFFL

3D structure

• PDB: 3jag Structural basis for stop codon recognition in eukaryotes.
• Chain: jj
• Resolution: 3.65 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	jj	R148 G149 S150 E151 Q153 S304 R306 R567 K579 I583 K584	R141 G142 S143 E144 Q146 S297 R299 R547 K559 I563 K564
BS02	SF4	jj	C29 C38 I39 C55 I56 G57 C58 C61	C26 C35 I36 C52 I53 G54 C55 C58
BS03	SF4	jj	C16 C21 C25 C65 P66 F67 L70	C13 C18 C22 C62 P63 F64 L67
BS04	ADP	jj	H13 G113 G115 K116 S117	H10 G110 G112 K113 S114

Gene Ontology

Molecular Function

• GO:0005506 iron ion binding
• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity
• GO:0043024 ribosomal small subunit binding

Biological Process

• GO:0000054 ribosomal subunit export from nucleus
• GO:0006413 translational initiation
• GO:0006415 translational termination

External links

• PDB: RCSB:3jag, PDBe:3jag, PDBj:3jag
• PDBsum: 3jag
• PubMed: 26245381
• UniProt: G1SG72