Structure of PDB 6hcf Chain j3

Receptor sequence

>6hcfj3 (length=86) Species: 9986 (Oryctolagus cuniculus)

TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPK

3D structure

• PDB: 6hcf ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
• Chain: j3
• Resolution: 3.9 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	j3	T2 K3 G4 T5 F8 G9 K10 R11 R12 N13 T15 H16 K25 H28 Q30 K31 K42 R43 K44 K46 Y47 N48 W49 S50 K52 R56 Y71 G81 K85	T1 K2 G3 T4 F7 G8 K9 R10 R11 N12 T14 H15 K24 H27 Q29 K30 K41 R42 K43 K45 Y46 N47 W48 S49 K51 R55 Y70 G80 K84
BS02	rna	j3	R20 R21 T59 G62 R63 M64 H66 R72 F74 R79 E80 T82 P84 K87	R19 R20 T58 G61 R62 M63 H65 R71 F73 R78 E79 T81 P83 K86
BS03	ZN	j3	C19 C22 C34	C18 C21 C33

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6hcf, PDBe:6hcf, PDBj:6hcf
• PDBsum: 6hcf
• PubMed: 30293783
• UniProt: U3KPD5|RL37_RABIT Large ribosomal subunit protein eL37 (Gene Name=RPL37)