Structure of PDB 8s8j Chain j

Receptor sequence

>8s8jj (length=267) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

TSHCRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELS
RRRIRSIQKLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKY
QKSKTVHSILRYCAEKFQIPLEELYKTIAWPLSRKFGHAYEAFKLSIIDE
TVWEGIEPPSKDVLDELKNYISKRLTPAVKIRADVEVSCFSYEGIDAIKD
ALKSAEDMSTEQMQVKVKLVAAPLYVLTTQALDKQKGIEQLESAIEKITE
VITKYGGVCNITMPPKA

3D structure

PDB

8s8j Structural basis of AUC codon discrimination during translation initiation in yeast.

Chain

Resolution

4.7 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	j	R53 R54 R55	R51 R52 R53
BS02	rna	j	R57 S58 I59 Q60 K61 R64 S110 Y114 Y172 K175 R185 V223 A224 P226	R55 S56 I57 Q58 K59 R62 S108 Y112 Y170 K173 R182 V220 A221 P223

External links

PDB	RCSB:8s8j, PDBe:8s8j, PDBj:8s8j
PDBsum	8s8j
PubMed	39193907
UniProt	P20459\|IF2A_YEAST Eukaryotic translation initiation factor 2 subunit alpha (Gene Name=SUI2)

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