Structure of PDB 8eti Chain j

Receptor sequence

>8etij (length=71) Species: 4896 (Schizosaccharomyces pombe)

KSHTICRRCGKRSFHIQKSTCACCGYPAAKTRSYNWGAKAKRRRTTGTGR
MSYLKKVHRSFKNGFRSGKPA

3D structure

• PDB: 8eti Chromatin localization of nucleophosmin organizes ribosome biogenesis.
• Chain: j
• Resolution: 3.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	j	H16 R25 S26 K31 A35 K43 T44 R45 Y47 N48 W49 K52 K54 R55 R56 H71 K75 N76 G77 R79 S80 G81	H3 R12 S13 K18 A22 K30 T31 R32 Y34 N35 W36 K39 K41 R42 R43 H58 K62 N63 G64 R66 S67 G68
BS02	rna	j	T17 R20 R21 C22 T59 G60 G62 R63 M64 S65 Y66 L67 F74 F78 R79 S80 G81 K82 P83	T4 R7 R8 C9 T46 G47 G49 R50 M51 S52 Y53 L54 F61 F65 R66 S67 G68 K69 P70
BS03	ZN	j	C19 C22 C34 C37	C6 C9 C21 C24

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0008270 zinc ion binding
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8eti, PDBe:8eti, PDBj:8eti
• PDBsum: 8eti
• PubMed: 36423630
• UniProt: P05733|RL37B_SCHPO Large ribosomal subunit protein eL37B (Gene Name=rpl3702)